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KMID : 1022820180090010010
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Journal of Multiple Sclerosis and Neuroimmunology
2018 Volume.9 No. 1 p.10 ~ p.13
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A Case of Stiff-person Syndrome with Hodgkin Disease
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Kim Ju-Hyeon
Park Jae-Hong
Choi Eun-Hyeok
Min Ju-Hong
Kim Byoong-Joon
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Abstract
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Stiff-person syndrome (SPS) is characterised by progressive rigidity and muscle spasms affecting the axial and limb muscles. Autoantibodies to the GABA-synthesizing enzyme glutamic acid decarboxylase, present in about 60-85% of patients, have indicated an autoimmune pathogenesis. Thus, other autoimmune diseases may occur or, rarely, neoplasms may occur together. We report a case of a patient diagnosed with SPS at the age of 20 who was diagnosed with Hodgkin disease 4 years later.
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KEYWORD
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Stiff-person syndrome, Autoimmune disease, Hodgkin disease
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